Description The Fluorescent Two-Hybrid (F2H®) Kits for p53-Mdm2 and for p53-Mdm4 respectively enable intracellular analysis of the interaction between the tumor suppressor p53 and its negative regulators Mdm2 or Mdm4.
Specificity Bait: GFP-p53 Prey: RFP-Mdm2 or RFP-Mdm4 Bait and prey interact.
Application Interaction analysis between the tumor suppressor p53 and its negative regulators Mdm2 or Mdm4: Monitor protein dynamics upon treatments Screen protein interaction inhibitors Click on left picture to activate images and animation