CatalogNo.: S-100F MW: 672.81
Description: Echelonoffersauniqueselectionofsphingosineanalogslabeledattheterminusofthealkylchainwithbiotinorfluorescentgroups.Allcompoundsaresynthesizedfromchiralprecursorsandareavailableaslyophilizedpowders. Echelon'salkyl-labeledsphingosinesaresynthesizedwiththenaturalerythrostereochemistryandmaintainsimilarpropertiesassphingosine.Forexample,labeledsphingosinesarephosphorylatedbysphingosinekinases(1&2)andcanbeusedinhighthroughputscreeningapplications.Inaddition,theyinduceaNiemanPicktypeC1diseasecellularphenoypeinRAWmacrophagesinthesamemannerasexogenouslyaddedsphingosine.
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