Recombinant mouse monoclonal antibody raised against human Amyloid beta 4-10.
Immunogen:
Original antibody is raised against a synthetic peptide of human Amyloid beta.
Reactivity:
Human
Specificity:
This antibody recognizes acid residues 4-10 of human Amyloid beta.
Form:
Liquid
Purification:
Protein A affinity purification
Isotype:
IgG2a, kappa
Recommend Usage:
ELISA (0.1 ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)Western Blot (1 ug/mL)The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS, pH 7.2 (0.02% Proclin 300).
Storage Instruction:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq
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