Rabbit polyclonal antibody raised against synthetic peptide of App.
Immunogen:
A synthetic peptide corresponding to C-terminus rat App.
Host:
Rabbit
Theoretical MW (kDa):
115
Reactivity:
Chicken, Dog, Human, Mouse, Primates, Rat
Form:
Liquid
Purification:
Affinity purification
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Recommend Usage:
Western Blot (1:1000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA)
Storage Instruction:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Datasheet:
Download
Publication Reference
1.
Regulation of amyloid precursor protein (APP) phosphorylation and processing by p35/Cdk5 and p25/Cdk5.Liu F, Su Y, Li B, Zhou Y, Ryder J, Gonzalez-DeWhitt P, May PC, Ni B.FEBS Lett. 2003 Jul 17;547(1-3):193-6.
Phosphorylation-dependent regulation of the interaction of amyloid precursor protein with Fe65 affects the production of beta-amyloid.Ando K, Iijima KI, Elliott JI, Kirino Y, Suzuki T.J Biol Chem. 2001 Oct 26;276(43):40353-61. Epub 2001 Aug 21.
Applications
Western Blot (Tissue lysate)
Western blot of rat hippocampal lysate showing specific immunolabeling of the ~115 KDa APP protein. Using App polyclonal antibody (Cat # PAB9629).
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