Rabbit polyclonal antibody raised against synthetic peptide of human ADAM17 (phospho T735).
Immunogen:
A synthetic peptide corresponding to amino acids 670-750 of human ADAM17 (phospho T735).
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Specificity:
This antibody detects endogenous levels of ADAM17 protein only when phosphorylated at T735.
Form:
Liquid
Purification:
Affinity purification
Isotype:
IgG
Recommend Usage:
ELISA (1:20000)Immunohistochemistry (1:100-300)Western Blot (1:500-2000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (50% glycerol, 0.5% BSA and 0.02% sodium azide).
Storage Instruction:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Datasheet:
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Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
Application Image
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
Gene Information
Entrez GeneID:
6868
Protein Accession#:
P78536
Gene Name:
ADAM17
Gene Alias:
CD156b,MGC71942,TACE,cSVP
Gene Description:
ADAM metallopeptidase domain 17
Omim ID:
603639
Gene Ontology:
Hyperlink
Gene Summary:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq
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