Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human prostate with ACPP polyclonal antibody (Cat # PAB30373) shows strong cytoplasmic positivity in glandular cells at 1:200-1:500 dilution.
This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway. [provided by RefSeq