| | CatalogNo.: P-9C2R
Description: Histone-H1-TMRislabeledwithareddye(tetramethylrhodamine)andhassuccessfullydeliveredthefollowingphosphoinositidesintocells:PtdIns(4,5)P2,PtdIns(3,4)P2,PtdIns(3,5)P2,PtdIns(3,4,5)P3,andtheirfluorescentanalogs.ThiscarriercanalsobefoundintheseShuttlePIPkits:P-9039,P-9034,P-9045,&P-9035.
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Toprovideourcustomerswithadditionaloptionsindesigningtheirowncell-deliveryapplications,Echelonoffersfluorescentandnon-fluorescentcarriersasstandaloneproductsoutsideourShuttlePIPsTMkits.Customerscanusethemosteffectivecarrierfortheirsystemalongwiththeindividualfluorescentornon-fluorescentphosphoinositidesoftheirchoice.
Providedas2x10nmoles StorageProtectfrommoistureandlightandstoreat-20°Cuntilreconstituted.Reconstitutewithwaterorotheraqueoussolutionsandstoreat4°Cinthedarkafterreconstitutingforupto3months.Multiplefreezethawingisnotrecommended.Note:phosphatebuffersarenotrecommendedandmayaltercomplexformationwithphosphoinositides.WedonotrecommendstoringcarriersandPIPstogetherascomplexes.FeaturedinReferences1)Ozaki,S.,D.B.DeWald,etal.(2000)."Intracellulardeliveryofphosphoinositidesandinositolphosphatesusingpolyaminecarriers."ProcNatlAcadSciUSA97(21):11286-11291. 2)Dewald,D.B.,S.Ozaki,etal.(2005)."Cellularcalciummobilizationinresponsetophosphoinositidedelivery."CellCalcium38(2):59-72. |