Protein A agarose resin consists of rProtein A covalently bound to cross-linked agarose beads. It provides a very stable bond that can greatly minimize leakage of the Protein A allowing for reuse of the affinity resin in several purification steps. Protein A Agarose resin is available in bulk from 5-100 ml quantities.
Protein A resin is good for the purification of a wide range of Immunoglobulins of different mammalian species and also certain IgG subclasses that have no other affinity (see additional information).
Protein A is a cell wall component of Staphylococcus aureus. It consists of a single polypeptide chain shaped as a cylinder, whichcontains five antibody–binding domains. These high affinity regions are specifically bonded to Fc region of the immunoglobulins(specially IgGs of different species).
Protein A is temperature stable and it retains its native conformation even in the presence of denaturing agents.
Storage/Handling: Store at 4°C. Do not freeze.
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