Description: | Vimentin: ELISA-VIDITEST anti-VIMENTIN kit is intended for the detection of IgG to vimentin in human serum. Vimentin, desmin, glial fibrillary acidic protein and peripherin are four proteins classified as type III intermediate filaments. Among the four proteins vimentin is the most widely distributed, it is a cytoskeletal part in leukocytes, blood vessel endothelial cells, in some epithelial cells and in cell of mesenchymal origin (fibroblasts). Serum autoantibodies against vimentin were found elevated in patients with neurofibromatosis type I, in patients with graft rejections of transplanted organs and in patients with interstitial lung fibrosis. |