Description: | Borrelia: ELISA-VIDITEST anti-Borrelia recombinant kits are intended for the detection of IgG and IgM antibodies to the pathogenic borrelia strains (B.afzelii, B. garinii and B. burgdorferi sensu stricto) in human serum, plasma, cerebrospinal fluid and synovial fluid. The detection of antibodies is one of the laboratory tests that help to diagnose Lyme disease (LD). Anti-borrelia IgM antibodies are detectable 3 weeks after infection with its maximum during the sixth week. Subsequently, the titer of IgM antibodies decreases and the IgG antibodies prevail. The detection of anti-borrelia antibodies is very important at the early stage of the disease since the typical symptoms are present only in a certain proportion of patients (e.g. erythema migrans is present in 50% of patients). The clinical symptoms of LD are similar to the symptoms in other diseases, therefore the serology is also of use in differential diagnosis of neuroinfections, arthropathies, carditis and skin diseases. ELISA-VIDITEST anti-C6 is an ELISA kit for the detection of anti-C6 antibodies in human serum. C6 is a highly specific conserved immunodominant 26 amino acid peptide derived from VlsE - outer surface lipoprotein of Borrelia burgdorferi. CE-IVD certified. |