Antigens for cellular immunity testing: Cellular immunity (CI) plays a dominant role in host control of herpesvirus infection. Its impairment may result in the development of chronic recurrent forms of the infections with poor prognosis for the patient. Virus-specific cellular immunity examination is important especially in the patients treated with immunosuppressive therapy (transplant recipients, oncological or autoimmune disease patients). It is beneficial also for vaccination or immunotherapy planning and efficiency monitoring. VZV – CI combi r.t.u. antigen contains native VZV proteins (extract from human embryonal fibroblasts infected with wild type VZV (strain M)) and a mixture of immunoactive peptides derived from immunodominant VZV proteins IE62 and IE63. It is intended for the specific stimulation of CD4+ and CD8+ T-lymphocytes.
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