| Description: | Embryonic Stem Cells (ESCs) are pluripotent cells derived from the inner cell mass of blastocysts. These cells are able to differentiate into all derivatives of the primary germ layers, including ectoderm, endoderm, and mesoderm, thus generating every cell type in the body. Different from most other stem cells, ESCs are capable of self-renewal indefinitely. Because of their plasticity and potentially unlimited capacity for self-renewal, ES cell therapies have been proposed for regenerative medicine and tissue replacement. OriCell™ Strain C57BL/6 Mouse ESCs maintain diploid karyotype after extended passages in vitro. These cells express specific clusters of different proteins for ESCs, and are capable of forming embryoid bodies in vitro and developing teratomas in nude mice. Cyagen OriCell™ Strain C57BL/6 Mouse ESCs are derived from the inner cell mass of strain C57BL/6 Mouse blastocysts (at 3.5 dpc) and cultured on γ-ray irradiated mouse embryonic fibroblasts as feeder cells in OriCell™ Mouse ESC Growth Medium. |
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