| Description: | Embryonic Stem Cells With RFP (ESCs/RFP) are pluripotent cells derived from the inner cell mass of blastocysts. These cells are able to differentiate into all derivatives of the primary germ layers, including ectoderm, endoderm, and mesoderm, thus generating every cell type in the body. Different from most other stem cells, ESCs/RFP are capable of self-renewal indefinitely. Because of their plasticity and potentially unlimited capacity for self-renewal, ES cell therapies hav e been proposed for regenerative medicine and tissue replacement. OriCell™ Strain 129 Mouse ESCs/RFP maintain diploid karyotype after extended passages in vitro. These cells express specific clusters of different proteins for ESCs/RFP, and are capable of forming embryoid bodies in vitro and developing teratomas in nude mice. Cyagen OriCell™ Strain 129 Mouse ESCs/RFP are derived from the inner cell mass of strain 129 mouse blastocysts (at 3.5 dpc) and cultured on γ-ray irradiated mouse embryonic fibroblasts as feeder cells in OriCell™ Mouse ESC Growth Medium, and then have been transfected with a lentiviral construct containing a RFP. expression motif, and been selected from a purified ESCs/RFP clone. |
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