Properties:
RelatedCategories | BloodandUrineChemistryAssayKits,CellBIOLOGy,EnzymaticKitsfortheQuantitationofNutrientsandMetabolites,MetabolismAssayKitsA-Z,Metabolomics |
Description:
FeaturesandBenefits
CompatIBLewithhigh-throughputliquidhandlingsystems.
Generaldescription
Xanthineisapurinebasepresentinbodyfluids,tissues,andplantscells.Itisalsofoundinurinarycalculi.Xanthineisformedbytheoxidationofhypoxanthineduringthedegradationofadenosinemonophosphate(AMP)touricacid.Xanthine/hypoxanthinemeasurementsinplasmaandurinehavebeenusedtomonitorallopurinoltherapy.Cerebrospinalfluid(CSF)xanthine/hypoxanthinelevelshavebeenusedastherapeuticguidesanddiseaseprogressionMarkersinhydrocephalus.
TheXanthine/HypoxanthineAssayKitisahighlysensitiveassayfordeterminingxanthine/hypoxanthinelevels(rangingfrom4-20nmole/wellforthecolorimetricassayand40-200pmole/wellforthefluorometricassay)inavarietyofbiologicalsamples.Xanthine/hypoxanthineconcentrationisdeterminedbyanenzymaticassay,whichresultsinacolorimetric(570nm)orfluorometric(λex=535/λem=587nm)product,proportionaltothexanthine/hypoxanthinepresent.
Note:Thefluorometricassayis~10timesmoresensitivethanthecolorimetricassay.
SuitABIlity
SuitableforthedetectionofXanthine/Hypoxanthineinavarietyofsamplessuchastissue,cells,andbodyfluids.
Safety:
Symbol
GHS07
Hazardstatements
H317-H319
Precautionarystatements
P280-P305+P351+P338
RIDADR
NONHforallmodesoftransport