Mouse (P75 knock-out) monoclonal antibody raised against native NGFR.
Immunogen:
Native purified NGFR from human WM245 melanoma cells.
Host:
Mouse
Reactivity:
Cat, Dog, Human, Pig, Rabbit, Sheep
Specificity:
This antibody recognizes p75NTR (low affinity neurotrophin receptor).
Form:
Liquid
Conjugation:
FITC
Isotype:
IgG
Recommend Usage:
Immunohistochemistry (2 ug/mL)Flow Cytometry (20 ug/mL)ELISA (1:5000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM Tris, 50 mM NaCl
Storage Instruction:
Store at 4°C.
Datasheet:
Download
Publication Reference
1.
Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism.Walker BR, Diefenbach KS, Parikh TN.Behav Brain Res. 2007 Jan 10;176(1):109-20. Epub 2006 Sep 12.
Applications
Immunohistochemistry
Immunofluorescence
Flow Cytometry
Application Image
Immunohistochemistry
Immunofluorescence
Flow Cytometry
Gene Information
Entrez GeneID:
4804
Gene Name:
NGFR
Gene Alias:
CD271,Gp80-LNGFR,TNFRSF16,p75(NTR),p75NTR
Gene Description:
nerve growth factor receptor (TNFR superfamily, member 16)
Omim ID:
162010
Gene Ontology:
Hyperlink
Gene Summary:
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq
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