Mouse monoclonal antibody raised against native NGFR.
Immunogen:
Native from human WM245 melanoma cells.
Host:
Mouse
Reactivity:
Cat, Dog, Human, Pig, Rabbit, Sheep
Specificity:
This antibody recognizes p75NTR (low affinity neurotrophin receptor).
Form:
Lyophilized
Purification:
Protein G purification
Isotype:
IgG1
Recommend Usage:
ELISA (1:5000)Flow Cytometry (20 ug/mL)Immunohistochemistry (2 ug/mL)The optimal working dilution should be determined by the end user.
Storage Buffer:
Lyophilized from PBS, pH 7.2-7.6 (0.1% trehalose, without preservative).
Storage Instruction:
Store at -20°C on dry atmosphere.Reconstitute with the addition of 100 uL of sterile water. Centrifuge to remove any insoluble material. After reconstitution, keep aliquots and store at -20°C for a higher stability, and at 2-8°C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability.Aliquot to avoid repeated freezing and thawing.
Datasheet:
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Publication Reference
1.
Inhibition within the nucleus tractus solitarius (NTS) ameliorates environmental exploration deficits due to cerebellum lesions in an animal model for autism.Walker BR, Diefenbach KS, Parikh TN.Behav Brain Res. 2007 Jan 10;176(1):109-20. Epub 2006 Sep 12.
Applications
Immunohistochemistry
Immunofluorescence
Flow Cytometry
Application Image
Immunohistochemistry
Immunofluorescence
Flow Cytometry
Gene Information
Entrez GeneID:
4804
Protein Accession#:
P08138
Gene Name:
NGFR
Gene Alias:
CD271,Gp80-LNGFR,TNFRSF16,p75(NTR),p75NTR
Gene Description:
nerve growth factor receptor (TNFR superfamily, member 16)
Omim ID:
162010
Gene Ontology:
Hyperlink
Gene Summary:
Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq
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