Mouse monoclonal antibody raised against synthetic peptide of Aqp1.
Immunogen:
A synthetic peptide corresponding to amino acids 249-269 of rat Aqp1.
Host:
Mouse
Reactivity:
Human, Mouse, Rat
Specificity:
The monoclonal antibody recognizes an epitope within the cytoplasmic domain of the water-specific channel aquaporin 1 (also known as AQP1 or CHIP-28). Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and the kidney. AQP1 is also expressed by the choroid plexus and various other tissues. The glycosylated forms of AQP1 range between 40-60kD in mass.
Form:
Liquid
Isotype:
IgG1
Recommend Usage:
Immunohistochemistry (Frozen sections) (1:500-1:1000)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)ELISA (1:1000-1:20000)Immunoprecipitation (1:1000-1:10000)Western Blot (1:1000-1:10000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In PBS (0.09% sodium azide, 0.1% BSA)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Datasheet:
Download
Publication Reference
1.
Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier.Szmydynger-Chodobska J, Strazielle N, Gandy JR, Keefe TH, Zink BJ, Ghersi-Egea JF, Chodobski A.J Cereb Blood Flow Metab. 2011 Aug 10. doi: 10.1038/jcbfm.2011.111. [Epub ahead of print]