Mouse monoclonal antibody raised against partial recombinant human ARG1.
Immunogen:
Recombinant protein corresponding to 87 residues around amino acids 1-150 of human ARG1.
Host:
Mouse
Theoretical MW (kDa):
35-38
Reactivity:
Human
Form:
Liquid
Purification:
Protein A/G purification
Isotype:
IgG3, kappa
Recommend Usage:
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)Immunofluorescence (1-2 ug/mL)Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL)Western Blot (0.5-1 ug/mL)The optimal working dilution should be determined by the end user.
Storage Buffer:
In 10 mM PBS.
Storage Instruction:
Store at -20 to -80°C.Aliquot to avoid repeated freezing and thawing.
Datasheet:
Download
Applications
Western Blot
Western Blot analysis of Lane 1: ARG1 recombinant protein fragment and Lane 2: human liver lysate with ARG1 monoclonal antibody, clone ARG1/1125 (Cat # MAB13324).
Arginase catalyzes the hydrolysis of arginine to ornithine and urea.At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function.The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle.Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq
Other Designations:
A-I,OTTHUMP00000017209,arginase, type I
Gene Pathway
Arginine and proline metabolism
Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid