Mouse monoclonal antibody raised against partial recombinant ABCG2.
Immunogen:
Recombinant protein corresponding to human ABCG2.
Host:
Mouse
Theoretical MW (kDa):
72
Reactivity:
Human, Monkey, Mouse
Form:
Liquid
Isotype:
IgG1
Recommend Usage:
ELISA (1:10000)Western Blot (1:500-1:2000)Immunofluorescence (1:200-1:1000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In ascites (0.03% sodium azide)
Storage Instruction:
Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Datasheet:
Download
Applications
Western Blot (Cell lysate)
Western blot analysis using ABCG2 monoclonal antibody, clone 1H2 (Cat # MAB10479) against HepG2 (1), COS-7 (2), Jurkat (3) and NIH/3T3 (4) cell lysate.
Immunofluorescence
Immunofluorescence analysis of HeLa cells using ABCG2 monoclonal antibody, clone 1H2 (Cat # MAB10479) (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
ATP-binding cassette, sub-family G (WHITE), member 2
Omim ID:
603756
Gene Ontology:
Hyperlink
Gene Summary:
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. [provided by RefSeq
Other Designations:
ABC transporter,ATP-binding cassette transporter G2,ATP-binding cassette, sub-family G, member 2,breast cancer resistance protein,mitoxantrone resistance protein,placenta specific MDR protein
购物车为空，快去购物吧！
4000-520-616
咨询顾问
特别 提示
Download
