Mouse monoclonal antibody raised against native A2M.
Immunogen:
Native purified human A2M.
Host:
Mouse
Reactivity:
Human
Form:
Liquid
Isotype:
IgG1, kappa
Recommend Usage:
Western Blot (1:2000)The optimal working dilution should be determined by the end user.
Storage Buffer:
In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
Storage Instruction:
Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Datasheet:
Download
Applications
Western Blot (Tissue lysate)
Immunoblot analysis of human plasma protein. Lane 1 : Alpha 2-macroglobulin isolated from human plasma. Lane 2 : Human plasma. (* N. S : Nonspecific band)
Enzyme-linked Immunoabsorbent Assay
Application Image
Western Blot (Tissue lysate)
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Enzyme-linked Immunoabsorbent Assay
Gene Information
Entrez GeneID:
2
Gene Name:
A2M
Gene Alias:
CPAMD5,DKFZp779B086,FWP007,S863-7
Gene Description:
alpha-2-macroglobulin
Omim ID:
103950, 104300
Gene Ontology:
Hyperlink
Gene Summary:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations:
-
Interactome
Gene Pathway
Complement and coagulation cascades
Related Disease
Alzheimer Disease
Alzheimer disease
Amyloidosis
Arthritis, Rheumatoid
Cardiovascular Diseases
Cognition Disorders
Dementia
Diabetes Complications
Diabetes Mellitus, Type 2
Disease Progression
Diseases in Twins
Edema
Essential Tremor
Essential tremor
Genetic Predisposition to Disease
Hepatitis C, Chronic
Kidney Failure, Chronic
Liver Cirrhosis
Macular Degeneration
... see more
Memory Disorders
Metabolic Syndrome X
Multiple Sclerosis
Myocardial Infarction
Neoplasms
Obesity
Obesity
Osteoporosis
Parkinson Disease
Parkinson disease
... hidden
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