Topoisomerase I (E. coli) catalyzes the relaxation of negatively supercoiled DNA. Topoisomerase I has also been implicated in knotting and unknotting DNA (1) and in linking complementary rings of single-stranded DNA into double-stranded rings (2). The intact holoenzyme is a 97 kDa protein.
Product Source
An E. coli strain containing the cloned topA gene
This product is related to the following categories:
DNA Repair Enzymes and Structure-specific Endonucleases Products