Cardiolipin (CL) is an important component of the prokaryotic and eukaryotic inner mitochondrial membrane. In humans, CL is made by cardiolipin synthase from phosphatidylglycerol and cytidinediphosphate-diacylglycerol. Monolysocardiolipin (MCL) is an intermediate in CL remodeling. Acetyl transferase tafazzin mutations impairing linoleic acid transfer to MCL are considered the main reason of Barth syndrome; and autoantibodies to MCL have been found in patients with anti-phospholipid syndrome and lupus. Fluorescent lipids have been used in TLC, electrophoresis, microplatefluorescent assays, and sub-cellular localization experiments.
Categories | Lipids |
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Filter | Biotinylated, Cardiolipin, Lysophospholipid |
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Molecular Formula | C63H118N4O19P2S |
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Molecular Weight (g/mol) | 1329.64 |
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Storage | -20 °C or below |
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