GZMB (Human) ELISpot Kit is a sandwich enzyme-based immunospot assay for the quantitative measurement of human GZMB.
Reactivity:
Human
Storage Instruction:
Store the kit at 4°C.
Protocol:
Protocol Download
Suitable Sample:
Cell
Sample Volume:
100 uL
Label:
Biotin-conjugated
Detection Method:
Colorimetric
Regulation Status:
For research use only (RUO)
Datasheet:
Download
Applications
Quantification
Application Image
Quantification
Gene Information
Entrez GeneID:
3002
Gene Name:
GZMB
Gene Alias:
CCPI,CGL-1,CGL1,CSP-B,CSPB,CTLA1,CTSGL1,HLP,SECT
Gene Description:
granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
Omim ID:
123910
Gene Ontology:
Hyperlink
Gene Summary:
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface "nonself" antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq