IL-17A/F (Human) ELISpot Kit is a sandwich enzyme-based immunospot assay for the quantitative measurement of human IL-17A/F.
Reactivity:
Human
Storage Instruction:
Store the kit at 4°C.
Protocol:
Protocol Download
Suitable Sample:
Cell
Sample Volume:
100 uL
Label:
Biotin-conjugated
Detection Method:
Colorimetric
Intra-Assay:
26.7%
Regulation Status:
For research use only (RUO)
Datasheet:
Download
Applications
Quantification
Application Image
Quantification
IL17A
IL17F
Gene Information
Entrez GeneID:
3605
Gene Name:
IL17A
Gene Alias:
CTLA8,IL-17,IL-17A,IL17
Gene Description:
interleukin 17A
Omim ID:
603149
Gene Ontology:
Hyperlink
Gene Summary:
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq
The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. [provided by RefSeq
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4000-520-616
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Protocol Download
