A2M (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human A2M.
Calibration Range:
1.953 to 500 ng/mL
Reactivity:
Human
Storage Instruction:
Store components of the kit at 4°C or -20°C as described in the protocol.
Protocol:
Protocol Download
MSDS:
Download
Suitable Sample:
Cell Culture Supernatant, CSF, Milk, Saliva
Sample Volume:
50 uL
Label:
Peroxidase-conjugated
Detection Method:
Colorimetric
Regulation Status:
For research use only (RUO)
Datasheet:
Download
Publication Reference
1.
Cross-talk between primary human renal tubular cells and endothelial cells in co-cultures.Tasnim F, Zink D.Am J Physiol Renal Physiol. 2012 Feb 8. [Epub ahead of print]
2.
Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis.Pineda-Salgado L, Craig EJ, Blank RB, Kessler DS.Gene Expr Patterns. 2005 Dec;6(1):3-10. Epub 2005 Nov 7.
3.
Glomerular deposition of alpha 2-macroglobulin in glomerular diseases.Yang AH, Chen JY.Nephrol Dial Transplant. 1997 Mar;12(3):465-9.
4.
Hepatocyte growth factor and acute phase proteins in patients with chronic liver diseases.Shiota G, Umeki K, Okano J, Kawasaki H.J Med. 1995;26(5-6):295-308.
Applications
Quantification
Application Image
Quantification
Gene Information
Entrez GeneID:
2
Gene Name:
A2M
Gene Alias:
CPAMD5,DKFZp779B086,FWP007,S863-7
Gene Description:
alpha-2-macroglobulin
Omim ID:
103950, 104300
Gene Ontology:
Hyperlink
Gene Summary:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations:
-
Interactome
Gene Pathway
Complement and coagulation cascades
Related Disease
Alzheimer Disease
Alzheimer disease
Amyloidosis
Arthritis, Rheumatoid
Cardiovascular Diseases
Cognition Disorders
Dementia
Diabetes Complications
Diabetes Mellitus, Type 2
Disease Progression
Diseases in Twins
Edema
Essential Tremor
Essential tremor
Genetic Predisposition to Disease
Hepatitis C, Chronic
Kidney Failure, Chronic
Liver Cirrhosis
Macular Degeneration
... see more
Memory Disorders
Metabolic Syndrome X
Multiple Sclerosis
Myocardial Infarction
Neoplasms
Obesity
Obesity
Osteoporosis
Parkinson Disease
Parkinson disease
... hidden
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Protocol Download
