ProductBackground:Heparinisahighlysulfatedglycosaminoglycanranginginsizefrom6to20kDa.Heparinispresentedinmastcell,liverandlungs.Althoughitsfunctionisunknown,itiswidelyusedasananticoagulanttopreventbloodclottinginvivoandinvitro.Forexample,heparinisusedaspreventativetreatmentfordeepveinthrombosisandpulmonaryembolism.Oversulfatedchondroitinsulfatecontaminationinrawheparinstocksusedforinjectableheparinmanufacturingwasdiscoveredin2008andresultedinamajorrecallofrelatedmedicalproducts.AccordingtotheFDA,itisbelievedatleast11deathswereassociatedwiththecontaminatedheparin-containingdevicesworldwide.Therefore,ensuringpurityofrawhepariniscriticalinmedicalheparinmanufacturing. Storage4°CReferencesCai,S.etal."ASelectiveProteinSensorforHeparinDetection."AnalBiochem.326(1),33-41(2004).
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