Antibody reactive against mammalian transfected lysate.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
MSDS:
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Interspecies Antigen Sequence:
Mouse (81); Rat (79)
Datasheet:
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Applications
Western Blot (Transfected lysate)
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Application Image
Western Blot (Transfected lysate)
Gene Information
Entrez GeneID:
64241
GeneBank Accession#:
HQ258492.1
Protein Accession#:
ADR83246.1
Gene Name:
ABCG8
Gene Alias:
GBD4,MGC142217,STSL
Gene Description:
ATP-binding cassette, sub-family G (WHITE), member 8
Omim ID:
210250, 605460
Gene Ontology:
Hyperlink
Gene Summary:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq
Other Designations:
ATP-binding cassette sub-family G member 8,ATP-binding cassette, subfamily G, member 8,sterolin 2
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4000-520-616
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