Transient overexpression cell lysate was tested with Anti-AADAT antibody (H00051166-B01) by Western Blots.SDS-PAGE GelAADAT transfected lysate.Western BlotLane 1: AADAT transfected lysate ( 47.3 KDa) Lane 2: Non-transfected lysate.
Storage Buffer:
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
MSDS:
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Interspecies Antigen Sequence:
Mouse (72); Rat (71)
Datasheet:
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Applications
Western Blot
Application Image
Western Blot
Gene Information
Entrez GeneID:
51166
GeneBank Accession#:
BC031068.1
Protein Accession#:
AAH31068.1
Gene Name:
AADAT
Gene Alias:
KAT2,KATII
Gene Description:
aminoadipate aminotransferase
Gene Ontology:
Hyperlink
Gene Summary:
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq
Other Designations:
L kynurenine/alpha aminoadipate aminotransferase,L-kynurenine/alpha-aminoadipate aminotransferase,alpha-aminoadipate aminotransferase,kynurenine aminotransferase II