Rabbit monoclonal antibody raised against a human AADAT peptide using ARM Technology.
Immunogen:
A synthetic peptide of human AADAT is used for rabbit immunization.Customer or Abnova will decide on the preferred peptide sequence.
Host:
Rabbit
Reactivity:
Human
Purification:
Protein A
Isotype:
IgG
Quality Control Testing:
Antibody reactive against human AADAT peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
1. Customer may provide cell or tissue lysate for antibody screening.2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Library Construction:
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression:
Overexpression vector and transfection into 293H cell line.
Deliverable:
Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
Datasheet:
Download
Applications
Western Blot (Transfected lysate)
Protocol Download
ELISA
Application Image
Western Blot (Transfected lysate)
ELISA
Gene Information
Entrez GeneID:
51166
GeneBank Accession#:
AADAT
Gene Name:
AADAT
Gene Alias:
KAT2,KATII
Gene Description:
aminoadipate aminotransferase
Gene Ontology:
Hyperlink
Gene Summary:
This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Two alternative transcripts encoding the same isoform have been identified, however, additional alternative transcripts and isoforms may exist. [provided by RefSeq
Other Designations:
L kynurenine/alpha aminoadipate aminotransferase,L-kynurenine/alpha-aminoadipate aminotransferase,alpha-aminoadipate aminotransferase,kynurenine aminotransferase II
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