Rabbit monoclonal antibody raised against a human AATF peptide using ARM Technology.
Immunogen:
A synthetic peptide of human AATF is used for rabbit immunization.Customer or Abnova will decide on the preferred peptide sequence.
Host:
Rabbit
Reactivity:
Human
Purification:
Protein A
Isotype:
IgG
Quality Control Testing:
Antibody reactive against human AATF peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
1. Customer may provide cell or tissue lysate for antibody screening.2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Library Construction:
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression:
Overexpression vector and transfection into 293H cell line.
Deliverable:
Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
Datasheet:
Download
Applications
Western Blot (Transfected lysate)
Protocol Download
ELISA
Application Image
Western Blot (Transfected lysate)
ELISA
Gene Information
Entrez GeneID:
26574
GeneBank Accession#:
AATF
Gene Name:
AATF
Gene Alias:
CHE-1,CHE1,DED
Gene Description:
apoptosis antagonizing transcription factor
Omim ID:
608463
Gene Ontology:
Hyperlink
Gene Summary:
The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis. [provided by RefSeq
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