Rabbit monoclonal antibody raised against a human AAK1 peptide using ARM Technology.
Immunogen:
A synthetic peptide of human AAK1 is used for rabbit immunization.Customer or Abnova will decide on the preferred peptide sequence.
Host:
Rabbit
Reactivity:
Human
Purification:
Protein A
Isotype:
IgG
Quality Control Testing:
Antibody reactive against human AAK1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note:
1. Customer may provide cell or tissue lysate for antibody screening.2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
Library Construction:
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression:
Overexpression vector and transfection into 293H cell line.
Deliverable:
Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
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