Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
MSDS:
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Datasheet:
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Publication Reference
1.
GATA2 regulates the erythropoietin receptor in t(12;21) ALL.Gaine ME, Sharpe DJ, Smith JS, Colyer HAA, Hodges VM, Lappin TR, Mills KI.Oncotarget. 2017 Aug 2;8(39):66061-66074. doi: 10.18632/oncotarget.19792. eCollection 2017 Sep 12.
Applications
Western Blot (Cell lysate)
EPOR monoclonal antibody (M01), clone 3D10. Western Blot analysis of EPOR expression in HeLa.
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Western Blot (Transfected lysate)
Western Blot analysis of EPOR expression in transfected 293T cell line by EPOR monoclonal antibody (M01), clone 3D10.Lane 1: EPOR transfected lysate (Predicted MW: 55.1 KDa).Lane 2: Non-transfected lysate.
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Western Blot (Recombinant protein)
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Immunoprecipitation
Immunoprecipitation of EPOR transfected lysate using anti-EPOR monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with EPOR MaxPab rabbit polyclonal antibody.
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Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EPOR is approximately 0.03ng/ml as a capture antibody.
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ELISA
Application Image
Western Blot (Cell lysate)
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Western Blot (Transfected lysate)
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Western Blot (Recombinant protein)
Immunoprecipitation
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Sandwich ELISA (Recombinant protein)
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ELISA
Gene Information
Entrez GeneID:
2057
GeneBank Accession#:
NM_000121
Protein Accession#:
NP_000112
Gene Name:
EPOR
Gene Alias:
MGC138358
Gene Description:
erythropoietin receptor
Omim ID:
133100, 133171
Gene Ontology:
Hyperlink
Gene Summary:
The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. [provided by RefSeq