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Abnova/ACTN4 (Human) Matched Antibody Pair/1kit/H00000081-AP44
  • Abnova/ACTN4 (Human) Matched Antibody Pair/1kit/H00000081-AP44

Abnova/ACTN4 (Human) Matched Antibody Pair/1kit/H00000081-AP44

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货号: H00000081-AP44
品牌: Abnova
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  • 使用说明
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      • Specification
      • Product Description:
      • This antibody pair set comes with matched antibody pair to detect and quantify protein level of human ACTN4.
      • Reactivity:
      • Human
      • Quality Control Testing:
      • Standard curve using recombinant protein ( H00000081-P01 ) as an analyte.QC Testing of H00000081-AP44Sandwich ELISA detection sensitivity ranging from 3 ng/ml to 100 ng/ml.
      • Supplied Product:
      • Antibody pair set content: 1. Capture antibody: mouse monoclonal anti-ACTN4, IgG2b Kappa (100 ug) 2. Detection antibody: biotinylated mouse monoclonal anti-ACTN4, IgG1 Kappa (50 ug) *Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.
      • Storage Instruction:
      • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
      • Interspecies Antigen Sequence:
      • Mouse (98%); Rat (98%)
      • Datasheet:
      • PDF DownloadDownload
      • Applications
      • ELISA Pair (Recombinant protein)
      • PDF DownloadProtocol Download
      • Application Image
      • ELISA Pair (Recombinant protein)
      • Gene Information
      • Entrez GeneID:
      • 81
      • Gene Name:
      • ACTN4
      • Gene Alias:
      • ACTININ-4,DKFZp686K23158,FSGS,FSGS1
      • Gene Description:
      • actinin, alpha 4
      • Omim ID:
      • 603278, 604638
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins.Alpha actinin is an actin-binding protein with multiple roles in different cell types.In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane.In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq
      • Other Designations:
      • actinin alpha4 isoform
      • Interactome
      • Interactome
      • Gene Pathway
      • Adherens junction
      • Arrhythmogenic right ventricular cardiomyopathy (ARVC)
      • Focal adhesion
      • Leukocyte transendothelial migration
      • Regulation of actin cytoskeleton
      • Systemic lupus erythematosus
      • Tight junction
      • Related Disease
      • Alport syndrome
      • Cardiovascular Diseases
      • Diabetes Mellitus, Type 1
      • Diabetes Mellitus, Type 2
      • Diabetic Nephropathies
      • Edema
      • Genetic Predisposition to Disease
      • Glomerulosclerosis, Focal Segmental
      • Kidney Diseases
      • Proteinuria
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