50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction:
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note:
Best use within three months from the date of receipt of this protein.
MSDS:
Download
Interspecies Antigen Sequence:
Mouse (62); Rat (63)
Datasheet:
Download
Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Application Image
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Gene Information
Entrez GeneID:
2
GeneBank Accession#:
NM_000014
Protein Accession#:
NP_000005.2
Gene Name:
A2M
Gene Alias:
CPAMD5,DKFZp779B086,FWP007,S863-7
Gene Description:
alpha-2-macroglobulin
Omim ID:
103950, 104300
Gene Ontology:
Hyperlink
Gene Summary:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations:
-
Interactome
Gene Pathway
Complement and coagulation cascades
Related Disease
Alzheimer Disease
Alzheimer disease
Amyloidosis
Arthritis, Rheumatoid
Cardiovascular Diseases
Cognition Disorders
Dementia
Diabetes Complications
Diabetes Mellitus, Type 2
Disease Progression
Diseases in Twins
Edema
Essential Tremor
Essential tremor
Genetic Predisposition to Disease
Hepatitis C, Chronic
Kidney Failure, Chronic
Liver Cirrhosis
Macular Degeneration
... see more
Memory Disorders
Metabolic Syndrome X
Multiple Sclerosis
Myocardial Infarction
Neoplasms
Obesity
Obesity
Osteoporosis
Parkinson Disease
Parkinson disease
... hidden
Related Product
DI0035
IL1B & A2M Protein Protein Interaction Antibody Pair
DI0036
KLK3 & A2M Protein Protein Interaction Antibody Pair
DI0037
IL10 & A2M Protein Protein Interaction Antibody Pair
DI0038
MMP2 & A2M Protein Protein Interaction Antibody Pair