Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer:
In 1x PBS, pH 7.4
Storage Instruction:
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
MSDS:
Download
Interspecies Antigen Sequence:
Mouse (62); Rat (63)
Datasheet:
Download
Applications
Western Blot (Recombinant protein)
Protocol Download
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged A2M is 3 ng/ml as a capture antibody.
Protocol Download
ELISA
In situ Proximity Ligation Assay (Cell)
Proximity Ligation Analysis of protein-protein interactions between IL1B and A2M. HeLa cells were stained with anti-IL1B rabbit purified polyclonal 1:1200 and anti-A2M mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
Application Image
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
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ELISA
In situ Proximity Ligation Assay (Cell)
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Gene Information
Entrez GeneID:
2
GeneBank Accession#:
NM_000014
Protein Accession#:
NP_000005.2
Gene Name:
A2M
Gene Alias:
CPAMD5,DKFZp779B086,FWP007,S863-7
Gene Description:
alpha-2-macroglobulin
Omim ID:
103950, 104300
Gene Ontology:
Hyperlink
Gene Summary:
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq
Other Designations:
-
Interactome
Gene Pathway
Complement and coagulation cascades
Related Disease
Alzheimer Disease
Alzheimer disease
Amyloidosis
Arthritis, Rheumatoid
Cardiovascular Diseases
Cognition Disorders
Dementia
Diabetes Complications
Diabetes Mellitus, Type 2
Disease Progression
Diseases in Twins
Edema
Essential Tremor
Essential tremor
Genetic Predisposition to Disease
Hepatitis C, Chronic
Kidney Failure, Chronic
Liver Cirrhosis
Macular Degeneration
... see more
Memory Disorders
Metabolic Syndrome X
Multiple Sclerosis
Myocardial Infarction
Neoplasms
Obesity
Obesity
Osteoporosis
Parkinson Disease
Parkinson disease
... hidden
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