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Abnova/mutaFISH™ EGFR T790M T790wt RNA Probes/1kit/FP0001
  • Abnova/mutaFISH™ EGFR T790M T790wt RNA Probes/1kit/FP0001

Abnova/mutaFISH™ EGFR T790M T790wt RNA Probes/1kit/FP0001

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货号: FP0001
品牌: Abnova
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  • 详情
  • 使用说明
  • 常见问题
      • Specification
      • Gene Info
      • Interactome
      • Pathway
      • Disease
      • Related Products
      • List All
      • Specification
      • Product Description:
      • mutaFISH™ EGFR T790M T790wt RNA Probes is designed to detect human EGFR T790M gene mutation on single strand RNA in cells using padlock probe and in situ rolling-circle amplification technology.
      • Supplied Product:
      • Content:1. RT EGFR T790 Primer2. mutaFISH™ EGFR T790M RNA Probe3. mutaFISH™ EGFR T790wt RNA Probe4. Detection Probe-Aqua 4315. Detection Probe-Texas Red X
      • Storage Instruction:
      • Store at -20°C.Aliquot to avoid repeated freezing and thawing.
      • Note:
      • We recommend mutaFISH™ RNA Accessory Kit (Catalog #: KA4915) which provides necessary reagents and enzymes for in situ reverse transcription, RNA digestion, mutaFISH™ hybridization, ligation and amplication prior to mutaFISH™.
      • Protocol:
      • PDF DownloadProtocol Download
      • Technology:
      • mutaFISH™ (mutation-specific Fluorescence In Situ Hybridization)
      • Comparison:
      • FISH Probes vs mutaFISH™ Probes
      • Fluorophore:
      • Aqua 431 (Excitation Peak (nm): 431; Emission Peak (nm): 480)Texas Red X (Excitation Peak (nm): 595; Emission Peak613)
      • Probe Position:
      • Regulatory Status:
      • For research use only (RUO)
      • Datasheet:
      • PDF DownloadDownload
      • Video:
      • Applications
      • mutation specific, Fluorescence In Situ Hybridization (Cells)
      • mutation specific, Fluorescence <em>In Situ</em> Hybridization (Cells)
      • mutaFISH™ staining was performed in situ in human H1975 cells captured by CytoQuest™ CR. EGFR T790M point mutation was detected via orange signal (Cy3), and EGFR T790wt was detected via red signal (Cy5).
      • Application Image
      • mutation specific, Fluorescence In Situ Hybridization (Cells)
      • mutation specific, Fluorescence <em>In Situ</em> Hybridization (Cells)
      • enlarge
      • Gene Information
      • Entrez GeneID:
      • 1956
      • Gene Name:
      • EGFR
      • Gene Alias:
      • ERBB,ERBB1,HER1,PIG61,mENA
      • Gene Description:
      • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
      • Omim ID:
      • 131550, 211980
      • Gene Ontology:
      • Hyperlink
      • Gene Summary:
      • The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
      • Other Designations:
      • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor
      • Interactome
      • Interactome
      • Gene Pathway
      • Adherens junction
      • Bladder cancer
      • Calcium signaling pathway
      • Colorectal cancer
      • Cytokine-cytokine receptor interaction
      • Dorso-ventral axis formation
      • Endocytosis
      • Endometrial cancer
      • Epithelial cell signaling in Helicobacter pylori infection
      • ErbB signaling pathway
      • Focal adhesion
      • Gap junction
      • Glioma
      • GnRH signaling pathway
      • MAPK signaling pathway
      • Melanoma
      • Non-small cell lung cancer
      • Pancreatic cancer
      • Pathways in cancer
      • Prostate cancer
      • Regulation of actin cytoskeleton
      • Related Disease
      • Adenocarcinoma
      • Adenocarcinoma, Bronchiolo-Alveolar
      • Adenocarcinoma, Mucinous
      • Adenocarcinoma, Papillary
      • Anus Neoplasms
      • Asthma
      • Asthma
      • Astrocytoma
      • Atherosclerosis
      • Barrett Esophagus
      • Bile Duct Neoplasms
      • Biliary Tract Neoplasms
      • Bipolar Disorder
      • Brain Neoplasms
      • Breast cancer
      • Breast Neoplasms
      • Bronchial Hyperreactivity
      • Carcinoma
      • Carcinoma, Adenosquamous
          • ... see more
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