BackgroundInformation | SerumAmyloidA3(SAA-3)isanacutephaseproteinproducedintheliver.Inresponsetoinjury,granulocytesandmacrophagessecretecytokineswhichmodulatetheproductionofacutephaseproteins.Manyoftheseproteins,suchasSAA-3,α1-acidglycoprotein(AGP),lipoclain24P3,plasminogenactivatorinhibitor-1(PAI-1)andPTX3aresecretedfromADIpocytesandareelevatedinvariousmetabolicdiseasestates. |