This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq
Other Designations:
-
Related Disease
Abortion, Habitual
Abortion, Spontaneous
Adenocarcinoma
Adenocarcinoma, Clear Cell
Adhesions
Aortic Aneurysm, Abdominal
Arthritis, Rheumatoid
Breast cancer
Breast Neoplasms
Carcinoma, Ductal, Breast
Carcinoma, Endometrioid
Carcinoma, Lobular
Cardiovascular Diseases
Colorectal Neoplasms
Connective Tissue Diseases
Diabetes Mellitus, Type 2
Ductus Arteriosus, Patent
Edema
Endometrial Neoplasms
... see more
Endometriosis
Esophageal Neoplasms
Fetal Diseases
Gender Identity
Genetic Predisposition to Disease
Hyperprolactinemia
Hypertension, Pregnancy-Induced
Infant, Premature, Diseases
Infection
Infertility, Female
Inflammation
Kidney Failure, Chronic
Leiomyoma
Lung Neoplasms
Lymphatic Metastasis
Lymphoma, Non-Hodgkin
Migraine Disorders
Musculoskeletal Diseases
Neoplasm Invasiveness
Neoplasms
Neoplasms, Cystic, Mucinous, and Serous
Neoplasms, Glandular and Epithelial
Neoplasms, Hormone-Dependent
Obesity
Obesity
Osteoporosis
Ovarian cancer
Ovarian Cysts
Ovarian Failure, Premature
Ovarian Neoplasms
Panic Disorder
Peritoneal Diseases
Polycystic Ovary Syndrome
Pregnancy Complications, Hematologic
Premature Birth
Prostate cancer
Prostatic Neoplasms
Proteinuria
Psychiatric Status Rating Scales
Puberty, Delayed
Puberty, Precocious
Pulmonary Disease, Chronic Obstructive
Skin Diseases
Stomach Neoplasms
Thrombophilia
Tobacco Use Disorder
Urinary Bladder Neoplasms
Uterine Diseases
Uterine Neoplasms
Vertigo
Werner syndrome
... hidden
Related Product
DP0290
PGR(Phospho S190) & PGR Protein Phosphorylation Antibody Pair