BODIPY TMR Phosphatidylinositol 3,4-bisphosphate is a water soluble analog of PI(3,4)P2 labeled with the orange fluorophore, Bodipy®-TMR, at the sn-1 position.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.
Bulk discounts available, please email echelon@echelon-inc.com for information.
| Categories | Lipids |
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| Filter | Fluorescent, Phosphoinositides, PI(3,4)P2 |
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| Excitation/Emission | 542/574 nm |
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| Molecular Formula | C78H147BF2N9O22P3 |
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| Molecular Weight (g/mol) | 1,704.78 |
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| Purity | >95% |
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| Storage | -20 °C or below, protect from light |
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