| | CatalogNo.: B-4201 MW: 205.08 Purity: >95% CAS: 66508-53-0
Description: Fosmidomycinisanaturallyoccurringantibioticthatinhibits1-deoxy-D-xylulose-5-phosphatereductoisomerase(DXR),anenzymeinthenon-mevanolatepathwayforisoprenoidbiosynthesis.Thenon-mevanolate,orMEP,pathwayisessentialingram-negative,somegram-positivebacteria,plants,andprotozoamakingitanattractivepathwaytotargetforantibioticssincemammalsusethemevalonatepathwaytosynthesizeisoprenoids.FosmidomycinhasbeentestedinhumansagainstPlasmodiumfalciparum(malaria)andshowntobeeffective. | |