| | CatalogNo.: B-0101 MW: 381.7 Purity: 99% CAS: 902779-59-3
Description: FPA-124isacell-permeableinhibitorofAkt(IC50=100nM),bindingtothePHandkinasedomains.ItinhibitscellproliferationinColo357,BxPC3,BT20,andPC3cancercelllineswithIC50valuesrangingfrom7-55nM.FPA-124inhibitedtumorgrowthinmicewithnegligIBLetoxicity. | |