NVP-231 is a potent, specific, and reversible Ceramide kinase (CerK) inhibitor (IC50= 12 nM in vitro) which competitively inhibits binding of ceramide. CerK is a key enzyme for controlling ceramide levels.
References
Graf C., et al., Targeting Ceramide Metabolism with a Potent and Specific Ceramide Kinase Inhibitor; Molecular Pharmacology, 2008, 74(4): 925-932
Categories | Biochemical Reagents |
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Filter | Inhibitor, Sphingolipid |
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CAS Number | 362003-83-6 |
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Molecular Formula | C25H25N3O2S |
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Molecular Weight (g/mol) | 431.55 |
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Purity | >95% |
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Storage | -20 °C or below |
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