Immunogen | RatGAT-1,C-terminus(aa588-599) |
Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
Host | Rabbit |
Specificity | RecognizesGABATransporter-1(GAT-1),C-terminus.Nocross-reactivitytotheC-terminiofothertransmittertransportersdetected. |
SpeciesReactivity | - Human
- Mouse
- Monkey
- Rat
- Rabbit
- Feline
|
AntibodyType | PolyclonalAntibody |
EntrezGeneNumber | |
GeneSymbol | - SLC6A1
- GABATR
- GAT1
- GABATHG
- GABT1
|
PurificationMethod | ImmunoAffinityPurified |
UniProtNumber | |
UniProtSummary | FUNCTION:SwissProt:P30531#TerminatestheactionofGABAbyitshighaffinitysodium-dependentreuptakeintopresynapticterminals. SIZE:599aminoacids;67015Da SUBUNIT:InteractswithMPP5(Bysimilarity). SUBCELLULARLOCATION:Cellmembrane;Multi-passmembraneprotein.Membrane;Multi-passmembraneprotein.Note=Localizedattheplasmamembraneandinasubsetofintracellularvesicles.Localizedatthepresynapticterminalsofinterneurons(Bysimilarity). DOMAIN:SwissProt:P30531ThePDZdomain-bindingmotifisinvolvedintheinteractionwithMPP5. SIMILARITY:Belongstothesodium:neurotransmittersymporter(SNF)family. MISCELLANEOUS:Thisproteinisthetargetofpsychomotorstimulantssuchasamphetaminesorcocaine. |
MolecularWeight | 67kDa |