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特别 提示
| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | PSEN1 (Phospho-Ser357) Antibody |
| Synonyms | AD3; AD3H; presenilin 1; PS-1; PS1; PSN1; PSNL1; S182 protein |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PSEN1 around the phosphorylation site of Ser357. |
| Immunogen Range | 323-372 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000 |
| Specificity | PSEN1 (Phospho-Ser357) Antibody detects endogenous levels of PSEN1 only when phosphorylated at Ser357. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | PSEN1 |
| Database Links |
Gene ID: 5663 Swiss-Prot #: P49768 OMIM #: 104311/600274/607822 Unigene #: Hs.3260 |
| Target Modification | Phospho |
| Modification Sites | H:S357 M:S357 R:S358 |
| Application Images | |
| Image 1 |
 Immunohistochemistry analysis of paraffin-embedded human brain, using PSEN1 (Phospho-Ser357) Antibody. The picture on the right is blocked with the phospho peptide. |
| Image 2 |
 Western blot analysis of lysates from RAW264.7 cells treated with UV 5', using PSEN1 (Phospho-Ser357) Antibody. The lane on the right is blocked with the phospho peptide. |
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