Note:
Theproductisforresearchuseonly,notforuseindiagnosticortherapeuticprocedures |
ProductName | IGF1R(Phospho-Tyr1161)Antibody |
Synonyms | CD221;IGF1R;Insulin-likegrowthfactorIreceptorprecursor;kinaseIGF1R |
Immunogen | TheantiserumwasproducedagainstsynthesizedpeptidederivedfromhumanIGF1RaroundthephosphorylationsiteofTyr1161. |
ImmunogenRange | 1131-1180 |
Clonality | Polyclonal |
ApplicationDilutions | WB:1:500~1:1000IHC:1:50~1:100ELISA:1:20000 |
Specificity | IGF1R(Phospho-Tyr1161)AntibodydetectsendogenouslevelsofIGF1RonlywhenphosphorylatedatTyr1161. |
Purification | Theantibodywaspurifiedfromrabbitantiserumbyaffinity-chromatographyusingphosphopeptide.Theantibodyagainstnon-phosphopeptidewasremovedbychromatographyusingcorrespondingnon-phosphopeptide. |
PhysicalForm | RabbitIgGinphosphatebufferedsaline(withoutMg2+andCa2+),pH7.4,150mMNaCl,0.02%sodiumazideand50%glycerol. |
Storage/StABIlity | Stableat-20°Cforatleast1year. |
NCBIGeneSymbol | IGF1R |
DatabaseLinks | GeneID: 3480 Swiss-Prot#: P08069/P06213 OMIM#: 147370/270450/147670 Unigene#: Hs.643120/Hs.653608/Hs.714012/Hs.465744 |
TargetModification | Phospho |
ModificationSites | H:Y1161/Y1185M:Y1163/Y1175R:Y1162/Y1186 |
ApplicationImages |
Image1 | Immunohistochemistryanalysisofparaffin-embeddedhumanbreastcarcinoma,usingIGF1R(Phospho-Tyr1161)Antibody.Thepictureontherightisblockedwiththephosphopeptide. |
Image2 | Westernblotanalysisoflysatesfrom293cellstreatedwithInsulin,usingIGF1R(Phospho-Tyr1161)Antibody.Thelaneontheleftisblockedwiththephosphopeptide. |