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| Note: The product is for research use only, not for use in diagnostic or therapeutic procedures |
|
| Product Name | Cortactin (Phospho-Tyr421) Antibody |
| Synonyms | Src substrate cortactin; Amplaxin; EMS1; CTTN; EMS1 |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Cortactin around the phosphorylation site of Tyr421. |
| Immunogen Range | 388-437 |
| Clonality | Polyclonal |
| Application Dilutions | WB: 1:500~1:1000 ELISA: 1:20000 |
| Specificity | Cortactin (Phospho-Tyr421) Antibody detects endogenous levels of Cortactin only when phosphorylated at Tyr421. |
| Purification | The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide. |
| Physical Form | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage/Stability | Stable at -20°C for at least 1 year. |
| NCBI Gene Symbol | CTTN |
| Database Links |
Gene ID: 2017 Swiss-Prot #: Q14247 OMIM #: 164765 Unigene #: Hs.596164 |
| Target Modification | Phospho |
| Modification Sites | H:Y421 M:Y421 R:Y384 |
| Application Images | |
| Image 1 |
 Western blot analysis of lysates from HeLa cells treated with H2O2, using Cortactin (Phospho-Tyr421) Antibody. The lane on the right is blocked with the phospho peptide. |
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