P-aminophenyl phosphate (pAPP) can be used as a substrate for alkaline phosphatase enzymatic reactions in order to electrochemically quantify ALP activity.
The enzymatic reaction results in the production of phenol, which can be quantified and used to analyze ALP concentrations.
ALP is a naturally occurring enzyme and can be found in human tissue in the liver, bone and intestines. Usual concentrations of ALP range between 25-100 IU/L. A significant spike outside of that range could act as a signal for many diseases.
Product Specificationsp-aminophenyl phosphate (pAPP)4-Aminophenyl phosphate monosodium salt hydrate
MOLECULAR BIOLOGY GRADE
Solid crystalline powder
Formula: C6H7NO4PNa
MW: 211.90 g/mol
Storage/Handling: Store at -15 °C, and protect from light.
PubMed Chemical ID: 71433871