This detergent is composed of a rigid bicyclic ring in the central region, and it has been found to be one of the best agents for GPCR stability. Due to the high rigidity of the molecule, this detergent is expected to facilitate protein crystallization and protein stabilization better than LMNG making it an excellent candidate for GPCR structural studies. This detergent has shown a promising behavior for visualization of GPCR complexes via CryoEM.