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Tocris/PF 04628935/6347/5/5 mg

价格: ¥828.00 市场价: 1380.00

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货号: 6347

品牌: Tocris

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Description:PotentghrelinreceptorinverseagoNIST

ChemicalName:1-[2-[[2-Chloro-4-(2H-1,2,3-triazol-2-yl)phenyl]methyl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thiazol-6-yl)ethanone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentghrelinreceptorinverseagonist(IC₅₀=4.6nM).Orallybioavailableandexhibitsreasonablebrainpenetration.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt	496.03
Formula	C₂₄H₂₆ClN₇OS
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	1383719-97-8
PubChemID	70682037
InChIKey	MTDYDDJVCIHZKH-UHFFFAOYSA-N
Smiles	ClC1=C(CN2CC3(CCN(C(CC4=CN(C=C(C)S5)C5=N4)=O)CC3)C2)C=CC(N6N=CC=N6)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	24.8	50
	ethanol	9.92	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight496.03.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.02mL	10.08mL	20.16mL
5mM	0.4mL	2.02mL	4.03mL
10mM	0.2mL	1.01mL	2.02mL
50mM	0.04mL	0.2mL	0.4mL

MolarityCalculator

Calculatethemass,volume,orconcentrationrequiredforasolution.

ReconstitutionCalculator

Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.

Volume(toaddtovial)

DilutionCalculator

Calculatethedilutionrequiredtoprepareastocksolution.