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Tocris/7α,25-Dihydroxycholesterol/6277/10/10 mg
  • Tocris/7α,25-Dihydroxycholesterol/6277/10/10 mg

Tocris/7α,25-Dihydroxycholesterol/6277/10/10 mg

价格: ¥4068.00 市场价: 6780.00
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货号: 6277
品牌: Tocris
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    • Description:HighlypotentGPR183(EBI2)agoNIST
      ChemicalName:(3β,7α)-Cholest-5-ene-3,7,25-triol
      Purity:≥98%(HPLC)
      BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

      BiologicalActivity

      HighlypotentGPR183(EBI2)agonist(EC50=140pM)andputativenaturalligandforGPR183.RegulatesmigrationofBandTcellsexpressingGPR183invivo.DesensitizesBcellsandreducestheirmovementtosplenicfollicles.

      TechnicalData

      M.Wt418.65
      FormulaC27H46O3
      StorageStoreat-20°C
      Purity≥98%(HPLC)
      CASNumber64907-22-8
      PubChemID11954197
      InChIKeyBQMSKLCEWBSPPY-IKVTXIKFSA-N
      SmilesO[C@H](C1)CC[C@@]2(C)C1=C[C@@H](O)[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@]4([H])[C@H](C)CCCC(C)(O)C

      Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

      AllTocrisproductsareintendedforlaboratoryresearchuseonly.

      SolubilityData

      SolventMaxConc.mg/mLMaxConc.mM
      Solubility
      DMSO4.1910mMwithgentlewarming

      PreparingStockSolutions

      Thefollowingdataisbasedontheproductmolecularweight418.65.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

      Concentration/SolventVolume/Mass1mg5mg10mg
      1mM2.39mL11.94mL23.89mL
      5mM0.48mL2.39mL4.78mL
      10mM0.24mL1.19mL2.39mL
      50mM0.05mL0.24mL0.48mL